[Quantitative changes of bacterial flora from the oral cavity and throat in children with acute lymphoblastic leukemia].

Quantitative investigations were carried on aerobic and anaerobic bacterial flora of oral cavity and throat in 44 children in the age of 5-10 years with acute lymphoblastic leukemia, intensively treated with cytostatics, and in 23 healthy children which served as a control group. Samples of saliva from leukemic children revealed significantly higher than in control group--presence of aerobic bacteria, particularly streptococci and enterococci. Material from throat was differing only in regard to staphylococci. Moreover, in children with leukemia, Gram-negative rods were present, which was not the case in the control group.