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急性结膜炎。夫西地酸粘性滴眼液与氯霉素的比较。

Acute conjunctivitis. A comparison of fusidic acid viscous eye drops and chloramphenicol.

作者信息

Hørven I

机构信息

Department of Ophthalmology, Oslo University, National Hospital, Rikshospitalet, Norway.

出版信息

Acta Ophthalmol (Copenh). 1993 Apr;71(2):165-8. doi: 10.1111/j.1755-3768.1993.tb04983.x.

Abstract

Fucidic acid viscous eye drops 1% given twice daily was compared with chloramphenicol eye drops 0.5% given 6 times daily in patients with acute conjunctivitis. Patients were recruited from 38 general practitioners in Norway. The mean duration of treatment was 6.6 days for Fucidic acid, 6.2 days for chloramphenicol. There was no major differences between the two groups in the bacteriological findings, and there was no significant difference in response to treatment. The use of fusidic acid in a carbomer vehicle as in Fucithalmic, has proved to give a long-lasting antibiotic concentration in the tear fluid, which allows the preferable twice daily application.

摘要

对急性结膜炎患者,比较了每日两次使用1%夫西地酸粘性滴眼液与每日六次使用0.5%氯霉素滴眼液的疗效。患者来自挪威38名全科医生处。夫西地酸治疗的平均疗程为6.6天,氯霉素为6.2天。两组的细菌学检查结果无重大差异,治疗反应也无显著差异。事实证明,如Fucithalmic中那样使用卡波姆载体的夫西地酸,能在泪液中产生持久的抗生素浓度,从而可优选每日两次用药。

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