Pfarrwaller A, Wild A, Hardmeier T
Schweiz Med Wochenschr. 1977 Feb 19;107(7):235-41.
Surgical excisional biopsies, needle biopsies and aspiration biopsies are at present the most frequently used technical procedures in the diagnosis of tumors or other pathologic conditions. An additional, lesser known method of obtaining tissue for microscopic examination with a high speed pneumatic drill biopsy device is described. Over a period of 29 months 118 biopsies have been performed in 99 patients for histologic examinations limited to breast lymph nodes, skin and scars, thyroid gland, bone and parotic gland. Only 8 (6.8%) out of 118 biopsies were inadequate for microscopic evaluation. The 110 (93.2%) histologically adequate biopsies showed 76 (64.4%) specimens with pathologic changes and 28 (23.7%) were correctly negative. Consequently, 104 (88.1%) of the biopsies performed gave correct results. 6 cases (5.1%) were false-negative. False-positive cases were not obtained. In view of the number of successful examinations with adequate results, it can be concluded that the method presented is a useful diagnostic tool. The procedure involves little stress for the patient and can be performed under local anesthesia on an out-patient basis.
手术切除活检、针吸活检和穿刺活检是目前肿瘤或其他病理状况诊断中最常用的技术手段。本文描述了另一种鲜为人知的方法,即使用高速气动钻活检装置获取组织进行显微镜检查。在29个月的时间里,对99例患者进行了118次活检,用于组织学检查,检查部位限于乳腺淋巴结、皮肤和瘢痕、甲状腺、骨骼和腮腺。118次活检中只有8次(6.8%)无法进行显微镜评估。110次(93.2%)组织学上足够的活检显示,76次(64.4%)标本有病理变化,28次(23.7%)结果正确为阴性。因此,所进行的活检中有104次(88.1%)结果正确。6例(5.1%)为假阴性,未出现假阳性病例。鉴于成功检查且结果充分的数量,可以得出结论,所介绍的方法是一种有用的诊断工具。该操作对患者造成的压力较小,可在局部麻醉下门诊进行。