Tricyclic dose requirements across pregnancy.
作者信息
Wisner K L, Perel J M, Wheeler S B
机构信息
Pregnancy and Infant/Parent Center, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15213.
出版信息
Am J Psychiatry. 1993 Oct;150(10):1541-2. doi: 10.1176/ajp.150.10.1541.
PMID:8379562
Abstract
In a series of eight pregnant women, the authors found that the doses of tricyclic antidepressants required to achieve remission of symptoms and adequate serum levels increased during the second half of pregnancy. During the final trimester, the mean dose required was 1.6 times the mean dose required when the patients were not pregnant.
摘要
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