Zhu W Y, Leonardi C, Penneys N S
Department of Dermatology, Nanjing Medical College.
Chin Med J (Engl). 1993 Feb;106(2):141-4.
Sections from 88 paraffin-embedded tissues identified histopathologically as condyloma acuminata were assayed for the presence of human papillomavirus (HPV) types 6, 11, 16, 18 and 33 using polymerase chain reaction followed by specific hybridization. HPV DNA sequences were found in all tissues of condyloma acuminata. HPV type 6 was present in 71 tissues, type 11 in 16, and type 16 in 2. One man was doubly infected with HPV types 6 and 16. No HPV types 18 and 33 were found. We conclude that condyloma acuminata is mainly produced by HPV types 6 and 11.
对88份经组织病理学鉴定为尖锐湿疣的石蜡包埋组织切片，采用聚合酶链反应及特异性杂交法检测人乳头瘤病毒（HPV）6、11、16、18和33型的存在情况。在所有尖锐湿疣组织中均发现了HPV DNA序列。71份组织中存在HPV 6型，16份中存在11型，2份中存在16型。1名男性同时感染了HPV 6型和16型。未发现HPV 18和33型。我们得出结论，尖锐湿疣主要由HPV 6型和11型引起。
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