Menczer J, Ben-Baruch G, Moran O, Lipitz S
Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Israel.
Obstet Gynecol. 1993 Jan;81(1):25-8.
To assess the feasibility of using cyst fluid CA 125 levels to distinguish between benign and malignant ovarian cystic neoplasms.
CA 125 levels were measured in ovarian cyst fluid and in serum obtained at surgery in 44 women with ovarian cystic tumors of epithelial origin (25 benign, 12 malignant, and seven borderline).
The median cyst fluid CA 125 level in malignant neoplasms (671 U/mL) was higher than in benign tumors (175 U/mL), and 86% of the malignant tumors contained levels higher than 100 U/mL in the cyst fluid, compared with only 62% of the benign tumors. However, these differences were not statistically significant.
Cyst fluid levels of CA 125 cannot be used to distinguish between benign and malignant ovarian cysts of epithelial origin.
评估利用囊液CA 125水平区分卵巢良性和恶性囊性肿瘤的可行性。
对44例上皮性卵巢囊性肿瘤患者(25例良性、12例恶性和7例交界性)手术时获取的卵巢囊液和血清进行CA 125水平检测。
恶性肿瘤囊液CA 125水平中位数(671 U/mL)高于良性肿瘤(175 U/mL),86%的恶性肿瘤囊液中CA 125水平高于100 U/mL,而良性肿瘤仅为62%。然而,这些差异无统计学意义。
CA 125囊液水平不能用于区分上皮性卵巢良性和恶性囊肿。