精神分裂症双胞胎的利手性：博克莱奇的观点正确吗？

Handedness in twins with schizophrenia: was Boklage correct?

作者信息

Torrey E F, Ragland J D, Gold J M, Goldberg T E, Bowler A E, Bigelow L B, Gottesman I I

机构信息

NIMH Neuropsychiatric Research Center, St. Elizabeth's Hospital, Washington, DC 20032.

出版信息

Schizophr Res. 1993 Mar;9(1):83-5. doi: 10.1016/0920-9964(93)90014-a.

DOI:10.1016/0920-9964(93)90014-a

PMID:8461274

Abstract

Boklage's report of increased non-right handedness among monozygotic twins with schizophrenia has been cited as evidence to support an association of abnormal brain lateralization with the development of schizophrenia. The present study found no such association. Two previous attempts to replicate Boklage's findings (Luchins et al. 1980; Lewis et al. 1989) also reported little support. Studies of twin handedness do not appear to support an association of brain lateralization and schizophrenia.

摘要

博克莱格关于患有精神分裂症的同卵双胞胎中非右利手比例增加的报告，被引为支持大脑侧化异常与精神分裂症发展之间存在关联的证据。而本研究并未发现此类关联。此前曾有两次试图重复博克莱格研究结果的尝试（卢钦斯等人，1980年；刘易斯等人，1989年），报告也几乎没有提供支持。对双胞胎利手情况的研究似乎并不支持大脑侧化与精神分裂症之间存在关联。