体外受精（IVF）患者血清和卵泡液中免疫球蛋白IgG、IgA、IgM、补体C3、C4以及铁蛋白和转铁蛋白的水平。

Immunoglobulins IgG, IgA, IgM, complement C3, C4 and ferritin and transferrin levels in serum and follicular fluid in IVF patients.

作者信息

Mantzavinos T, Dalamanga N, Hassiakos D, Dimitriadou F, Gregoriou O, Zourlas P A

机构信息

2nd Dept. of Ob-Gyn, University of Athens, Areteion Hospital, Greece.

出版信息

Clin Exp Obstet Gynecol. 1993;20(1):32-6.

PMID:8462185

Abstract

Serum and follicular fluid immunoglobulin (IgG, IgA, IgM) and complement (C3, C4), as well as transferrin and ferritin concentrations were measured in 82 consecutive IVF patients (Pregnant: Group A, and non pregnant: Group B). Higher serum concentrations were observed in complement in all Immunoglobulins but IgM which was found to be significantly lower in follicular fluid in both groups. Also there were no statistically significant differences observed for transferrin and ferritin levels in either compartment or among the groups. No correlation was found for the above parameters and the in vitro fertilization outcome in terms of oocytes retrieved, fertilized and embryos implanted.

摘要

对82例连续接受体外受精的患者（怀孕组：A组；未怀孕组：B组）测定了血清和卵泡液中的免疫球蛋白（IgG、IgA、IgM）、补体（C3、C4）以及转铁蛋白和铁蛋白的浓度。除IgM外，所有免疫球蛋白的补体血清浓度均较高，而两组卵泡液中的IgM均显著较低。此外，转铁蛋白和铁蛋白水平在任何一个腔室或组间均未观察到统计学上的显著差异。未发现上述参数与所获卵母细胞、受精及植入胚胎方面的体外受精结果之间存在相关性。