Fallahzadeh H
Department of Surgery, University of Louisville, Kentucky.
Am Surg. 1993 Jan;59(1):20-2.
We retrospectively reviewed all the operative procedures performed for benign peptic ulcer disease in a regional hospital during the past 6 years. The indications were hemorrhage, perforation, obstruction, chronicity, and gastrocolic. No operation for chronicity has been performed since 1986. Only in perforation was there a statistical difference between male and female. Two hundred forty-six patients were admitted for bleeding, 108 were given transfusions and 38 required operative intervention for control of bleeding. The average units of blood given to patients with bleeding, who underwent operative intervention and recovered, was 7.2. The 6 deaths in this group were in patients who received 15.7 units of blood. Of these, none survived. Twenty patients with perforated ulcers were successfully treated with gastric resection with vagotomy. One patient with a perforated ulcer had primary suture repair, another had vagotomy and pylorplasty. Both required gastric resection because of obstruction and reperforation, respectively. Gastric resection with truncal vagotomy successfully corrected obstruction in 18 patients and chronicity in 9 patients, without mortality. Death from hemorrhage is directly related to delay in operative intervention. With the availability of effective medication for control of gastric acidity, the need for selective vagotomy or elective operative procedure for ulcers is fast disappearing.
我们回顾性研究了一家地区医院在过去6年中针对良性消化性溃疡疾病所实施的所有手术操作。手术指征包括出血、穿孔、梗阻、慢性溃疡以及胃结肠瘘。自1986年以来未进行过慢性溃疡手术。仅在穿孔方面,男性和女性之间存在统计学差异。246例患者因出血入院,108例接受输血治疗,38例需要手术干预以控制出血。接受手术干预并康复的出血患者平均输血单位数为7.2。该组中有6例死亡患者接受了15.7个单位的输血,无一存活。20例穿孔性溃疡患者通过胃切除加迷走神经切断术成功治愈。1例穿孔性溃疡患者接受了一期缝合修复,另1例接受了迷走神经切断术和幽门成形术。这两例患者分别因梗阻和再次穿孔而需要进行胃切除术。胃切除加迷走神经干切断术成功纠正了18例患者的梗阻和9例患者的慢性溃疡,无死亡病例。出血导致的死亡与手术干预延迟直接相关。随着有效控制胃酸药物的出现,溃疡患者对选择性迷走神经切断术或择期手术的需求正在迅速消失。