Amarenco G, Kerdraon J
Service de Rééducation, Hôpital Robert Ballanger, Aulnay-sous-Bois.
Prog Urol. 1993 Feb;3(1):21-6.
The existence of urethral fatiguability was demonstrated by a sphinctometric study in 30 women. Comparison of the baseline urethral pressure values and after 6 maximal coughs demonstrated a mean reduction in urethral pressure of 40% (range: 24.5 to 90%) in 10 out of 18 women with stress incontinence. This decreased pressure lasted for several seconds. Spectral analysis of the electromyographic recording of the striated urethral sphincter under basal conditions and then after coughing confirmed the intervention of the striated and periurethral musculature with a marked quantitative decrease in the electrical activity of the sphincter. The clinical pathophysiological, prognostic and therapeutic implications of this new concept are discussed.
一项针对30名女性的尿道压力测定研究证实了尿道疲劳性的存在。对18名压力性尿失禁女性中的10名进行基线尿道压力值与6次最大咳嗽后压力值的比较，结果显示尿道压力平均降低了40%（范围：24.5%至90%）。这种压力降低持续了数秒。对基础条件下以及咳嗽后尿道横纹括约肌肌电图记录进行频谱分析，证实了横纹肌和尿道周围肌肉组织的参与，同时括约肌电活动明显定量减少。本文讨论了这一新概念的临床病理生理学、预后及治疗意义。
