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腹腔镜胆囊切除术的胆道并发症

Biliary complications of laparoscopic cholecystectomy.

作者信息

Cates J A, Tompkins R K, Zinner M J, Busuttil R W, Kallman C, Roslyn J J

机构信息

Department of Surgery, UCLA School of Medicine.

出版信息

Am Surg. 1993 Apr;59(4):243-7.

PMID:8489086
Abstract

Laparoscopic cholecystectomy has rapidly become the preferred treatment for symptomatic gallstones. Although this procedure has certain advantages over open cholecystectomy, concern has been expressed regarding the potential for bile duct injuries. In an effort to understand the scope of this problem, a retrospective review was performed of all patients referred to UCLA after having sustained biliary injuries during laparoscopic cholecystectomy. Over a 14-month period, 10 patients were referred to UCLA with 12 major bile duct injuries. One patient had a false positive cholangiogram leading to an unnecessary biliary-enteric bypass and subsequent dehiscence, resulting in a biliary fistula. Six patients were referred on an acute basis, whereas four patients underwent attempted biliary reconstruction at outside facilities and were ultimately referred with either a biliary stricture or a fistula. Review of cholangiograms suggested that bile duct anomalies were present in five patients. There did not appear to be a relationship between the use of either electrocautery or laser and bile duct injuries. To date eight patients have been successfully managed via Roux-en-Y hepaticojejunostomies, with a mortality rate of 0%. Although the exact frequency cannot be ascertained from the current study, our data demonstrate that major biliary complications do occur during laparoscopic cholecystectomy. Most of these injuries, however, can be safely and successfully treated with surgical biliary reconstruction. Early diagnosis and treatment with liberal use of intraoperative cholangiography and a low threshold for conversion to open laparotomy appears to be associated with a more favorable outcome.

摘要

腹腔镜胆囊切除术已迅速成为有症状胆结石的首选治疗方法。尽管该手术与开腹胆囊切除术相比有一定优势,但人们对胆管损伤的可能性表示担忧。为了解这一问题的范围,对所有在腹腔镜胆囊切除术中发生胆管损伤后转诊至加州大学洛杉矶分校的患者进行了回顾性研究。在14个月的时间里,有10名患者因12处主要胆管损伤转诊至加州大学洛杉矶分校。1例患者胆管造影出现假阳性,导致不必要的胆肠吻合术及随后的吻合口裂开,形成胆瘘。6例患者为急性转诊,而4例患者在外部机构尝试进行胆管重建,最终因胆管狭窄或胆瘘转诊。胆管造影复查显示5例患者存在胆管异常。电灼或激光的使用与胆管损伤之间似乎没有关系。迄今为止,8例患者已通过Roux-en-Y肝空肠吻合术成功治疗,死亡率为0%。尽管目前的研究无法确定确切的发生率,但我们的数据表明,腹腔镜胆囊切除术中确实会发生主要的胆管并发症。然而,大多数此类损伤可以通过手术胆管重建得到安全、成功的治疗。早期诊断和治疗,术中广泛使用胆管造影并降低转为开腹手术的阈值,似乎与更有利的结果相关。

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