胼胝体发育不全儿童的脑电图。静息状态下的相干值：左半球代偿机制？
The EEG in acallosal children. Coherence values in the resting state: left hemisphere compensatory mechanism?
作者信息
Koeda T, Knyazeva M, Njiokiktjien C, Jonkman E J, De Sonneville L, Vildavsky V
机构信息
Division of Child Neurology, Tottori University Faculty of Medicine, Yonago, Japan.
出版信息
Electroencephalogr Clin Neurophysiol. 1995 Dec;95(6):397-407. doi: 10.1016/0013-4694(95)00171-9.
Resting EEG interhemispheric and intrahemispheric coherences (ICoh and HCoh) in the theta, alpha and beta bands were studied in 7 patients with agenesis of the corpus callosum (5 children, aged 10-14 years, and 2 adults) and 2 groups of sex- and age-matched normal children and adults (42 subjects). In patients the ICohs (F3/F4, C3/C4, P3/P4, O1/O2) were lower than in the normal sample. The ICoh decrease, corresponding with the completeness of commissural agenesis, showed the essential role of the corpus callosum in interhemispheric EEG synchronization. A remarkable new fact was found, namely lower right hemisphere HCoh in the acallosal patients in comparison to the normals, suggesting reduced connectivity of the right hemisphere. It is assumed that the deviant HCoh patterns in the patients, most pronounced in the beta band, are indicative of compensatory left hemisphere mechanisms, accounting for a specific brain plasticity phenomenon in acallosal subjects.
对7例胼胝体发育不全患者（5名儿童，年龄在10至14岁之间，2名成人）以及两组性别和年龄匹配的正常儿童和成人（42名受试者），研究了静息脑电图在θ、α和β波段的半球间和半球内相干性（ICoh和HCoh）。患者的ICoh（F3/F4、C3/C4、P3/P4、O1/O2）低于正常样本。与连合部发育不全的完整性相对应的ICoh降低，表明胼胝体在半球间脑电图同步中起着重要作用。发现了一个显著的新事实，即与正常人相比，无胼胝体患者右半球的HCoh较低，表明右半球的连接性降低。据推测，患者中异常的HCoh模式在β波段最为明显，这表明存在代偿性左半球机制，这是无胼胝体受试者中一种特定的脑可塑性现象。
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