McBride W, Richter G C, Frontin K, Sung J
Department of Medicine, Morehouse School of Medicine, Atlanta, GA 30310-1495, USA.
J Natl Med Assoc. 1995 Dec;87(12):881-6.
There is a higher incidence of colorectal cancer in young African-American patients compared with white Americans. This study examines the incidence, demographic pattern, and distribution of neoplastic lesions identified by flexible sigmoidoscopy in an African-American population. A sample of charts was reviewed from an urban gastroenterology practice that serves predominantly African Americans. A total of 455 patients were found who underwent flexible sigmoidoscopy. The sample included 391 symptomatic patients and 64 asymptomatic patients. Two hundred fifty-five patients were < 50 years old and 200 patients were > or = 50 years. More neoplastic lesions were found among older patients (21 patients: 14 with polyps and 7 cancers) than among younger patients (7 patients: 3 with polyps and 4 cancers); the difference of all positive findings between the two groups was significant. However, the cancerous rate for younger patients was not statistically different from that for older patients. These findings suggest that young African-American patients with colorectal symptoms should undergo aggressive approaches to detect cancer early.
与美国白人相比,年轻非裔美国患者患结直肠癌的几率更高。本研究调查了通过乙状结肠镜检查确定的非裔美国人群中肿瘤性病变的发病率、人口统计学模式及分布情况。研究回顾了一家主要服务非裔美国人的城市胃肠病诊所的病历样本。共发现455例接受乙状结肠镜检查的患者。样本包括391例有症状患者和64例无症状患者。255例患者年龄小于50岁,200例患者年龄大于或等于50岁。老年患者中发现的肿瘤性病变(21例:14例息肉和7例癌症)比年轻患者(7例:3例息肉和4例癌症)更多;两组所有阳性结果的差异具有显著性。然而,年轻患者的癌症发生率与老年患者相比无统计学差异。这些发现表明,有结直肠症状的年轻非裔美国患者应采取积极措施以早期发现癌症。