Leys A M
Service d'Ophtalmologie, section Rétine Médicale, U.Z. Leuven.
Bull Soc Belge Ophtalmol. 1995;256:49-59.
In patients with diabetic nephropathy retinopathy is always present and proliferative retinopathy is common. Retinopathy tends to deteriorate as renal failure develops particularly in patients with poorly controlled blood pressure and in patients in whom no retinal treatment has been given before development of renal failure. Treatment of hypertension and of end stage renal failure will improve macular edema and stabilize vision. As the progression of diabetic retinopathy is independent of diabetic nephropathy and not reversed by treatment of nephropathy, further follow-up and treatment of diabetic retinopathy are imperative. In recent years medical treatment of arterial hypertension and facilities for dialysis and kidney transplantation have become available, and patients are now treated at a much earlier stage of their renal disease. Consequently, were are seeing fewer patients with renal failure and severe hypertensive fundus changes. Nevertheless, arterial hypertension is still a very important problem in diabetic patients with and without nephropathy and complications of atherosclerosis are common as a result of chronic hypertension and hyperlipidemia.
糖尿病肾病患者总是伴有视网膜病变,增殖性视网膜病变也很常见。随着肾衰竭的发展,视网膜病变往往会恶化,尤其是在血压控制不佳的患者以及在肾衰竭发生前未接受过视网膜治疗的患者中。高血压和终末期肾衰竭的治疗将改善黄斑水肿并稳定视力。由于糖尿病视网膜病变的进展独立于糖尿病肾病,且不会因肾病治疗而逆转,因此对糖尿病视网膜病变进行进一步随访和治疗势在必行。近年来,动脉高血压的药物治疗以及透析和肾脏移植设施已经具备,现在患者在肾病的更早阶段就接受治疗。因此,我们看到肾衰竭和严重高血压眼底改变的患者越来越少。然而,动脉高血压在有或没有肾病的糖尿病患者中仍然是一个非常重要的问题,并且由于慢性高血压和高脂血症,动脉粥样硬化并发症很常见。