Ramasoota P, Intaratitaya T
National Institute for Leprosy Research, Tokyo, Japan.
Nihon Rai Gakkai Zasshi. 1995 Nov;64(3):214-9. doi: 10.5025/hansen1977.64.214.
This paper report the progress and impact of MDT implementation to leprosy control in Thailand since 1984 until 1994. By ten years of MDT implementation, number of registered cases dropped from 44,406 in 1984 to only 4,878 cases in 1994. Which made prevalence rate declined 90% from 8.8 to 0.83 per 10,000 population, the detection rate of new case declined from 6.2 to 1.97 per 100,000 population. Total 39,372 cases have been completely covered by MDT and 22,821 cases are under post MDT surveillance with the low relapse rate only 1.46% other indicators showing natural decline of leprosy were increasing in proportion of multibacillary leprosy and mean age at onset of new case of leprosy together with decreasing in proportion of children among new case. Other impact of MDT showing increasing trend of proportion of new case of patient who voluntarily attend treatment centers. However, there were still no satisfactory impact on decreasing in proportion of deformity and duration since onset to the first detection of new case of leprosy.
本文报告了1984年至1994年泰国实施多药联合化疗(MDT)对麻风病控制的进展和影响。经过十年的MDT实施,登记病例数从1984年的44406例降至1994年的仅4878例。这使得患病率从每10000人口8.8例下降90%至0.83例,新病例发现率从每100000人口6.2例降至1.97例。共有39372例病例已完全接受MDT治疗,22821例病例处于MDT后监测中,复发率仅为1.46%。显示麻风病自然下降的其他指标包括多菌型麻风病比例增加、麻风病新发病例的平均发病年龄增加以及新病例中儿童比例下降。MDT的其他影响包括自愿前往治疗中心的新病例患者比例呈上升趋势。然而,在降低麻风病新病例的畸形比例以及从发病到首次发现的时间方面,仍未产生令人满意的影响。