Spiegel G W, Swiger F K
Department of Pathology, Medical University of South Carolina, Charleston, 29425, USA.
Gynecol Oncol. 1996 May;61(2):275-81. doi: 10.1006/gyno.1996.0139.
The seventh reported case of luteinized thecoma with sclerosing peritonitis is described. Unlike the other reported patients with this condition, the patient presented with a short history of secondary amenorrhea, a subsequent acute abdomen, and an absence of abdominal distention and ascites. The tumor had undergone extensive hemorrhagic necrosis secondary to infarction, and the patient's amenorrhea may have been secondary to the release of steroid hormones from the necrotic cells. The presence of extensive necrosis and a brisk mitotic rate raised the suspicion of a malignant thecoma, but the finding of subserosal fibrosis in the biopsied omental tissue led to the diagnosis of a benign luteinized thecoma with sclerosing peritonitis.
本文描述了第七例伴有硬化性腹膜炎的黄素化卵泡膜瘤病例。与其他报道的患有这种疾病的患者不同,该患者表现为继发性闭经病史短,随后出现急腹症,且无腹胀和腹水。肿瘤因梗死继发广泛出血性坏死,患者的闭经可能继发于坏死细胞释放的甾体激素。广泛坏死和活跃的有丝分裂率增加了恶性卵泡膜瘤的怀疑,但活检的网膜组织中浆膜下纤维化的发现导致诊断为伴有硬化性腹膜炎的良性黄素化卵泡膜瘤。