躁狂症、精神病与抗精神病药物

Mania, psychosis, and antipsychotics.

作者信息

McElroy S L, Keck P E, Strakowski S M

机构信息

Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267-0559, USA.

出版信息

J Clin Psychiatry. 1996;57 Suppl 3:14-26; discussion 47-9.

PMID:8626366

Abstract

Although psychotic symptoms often occur in the manic phase of bipolar disorder, psychotic mania has been and continues to be frequently misdiagnosed as schizophrenia or other psychotic illnesses. In addition, the role of antipsychotic agents in the acute and maintenance treatment of psychotic mania remains unclear. In this paper, we present an overview of studies of psychosis in mania. We also review studies of conventional and newer antipsychotic agents in the acute and maintenance treatment of psychotic mania to help clarify the role of these agents in treating this illness.

摘要

虽然精神病性症状常在双相情感障碍的躁狂相出现，但精神病性躁狂一直以来且仍经常被误诊为精神分裂症或其他精神病性疾病。此外，抗精神病药物在精神病性躁狂的急性期和维持期治疗中的作用仍不明确。在本文中，我们概述了关于躁狂症中精神病性症状的研究。我们还回顾了传统和新型抗精神病药物在精神病性躁狂急性期和维持期治疗的研究，以帮助阐明这些药物在治疗该疾病中的作用。