Fleisher L A, Eagle K A
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Ann Intern Med. 1996 Apr 15;124(8):767-72. doi: 10.7326/0003-4819-124-8-199604150-00011.
The preoperative evaluation of the cardiac patient having noncardiac surgery offers an opportunity to identify occult and further define known cardiovascular disease to modify both perioperative and long-term care. The baseline probability of cardiovascular disease should initially be assessed using clinical variables and identifying unstable symptoms, including unstable angina and congestive heart failure. The decision about whether to obtain noninvasive testing to further define cardiovascular status should be made on the basis of the testing's potential to modify perioperative care, the prior probability of advanced coronary disease based on clinical history, and the magnitude of the surgical procedure. Noninvasive testing is best done in selected patients who are at moderate clinical risk. Otherwise, testing loses its predictive value because of a high incidence of false-negative and false-positive results. Quantitative imaging can also be used to identify those patients in whom coronary angiography is indicated. The value of coronary revascularization before noncardiac surgery has not been studied in a randomized, prospective manner, but several cohort studies have suggested that patients who survive coronary artery bypass grafting have decreased risk during subsequent noncardiac surgery. Given the potential short-term increase in morbidity from two surgical procedures, it is prudent to reserve coronary revascularization before noncardiac surgery for those patients in whom it is associated with improved long-term survival. If coronary revascularization is reserved for these patients, then the overall evaluation should prove cost-effective from the perspective of both perioperative and long-term cardiovascular care.
对接受非心脏手术的心脏病患者进行术前评估,为识别隐匿性心血管疾病以及进一步明确已知的心血管疾病提供了契机,以便调整围手术期和长期护理方案。应首先利用临床变量并识别不稳定症状(包括不稳定型心绞痛和充血性心力衰竭)来评估心血管疾病的基线概率。关于是否进行无创检查以进一步明确心血管状况的决定,应基于该检查对调整围手术期护理的潜在作用、根据临床病史判断的晚期冠状动脉疾病的先验概率以及手术的规模。无创检查最好在具有中度临床风险的特定患者中进行。否则,由于假阴性和假阳性结果的发生率较高,检查将失去其预测价值。定量成像也可用于识别那些需要进行冠状动脉造影的患者。非心脏手术前进行冠状动脉血运重建的价值尚未在前瞻性随机研究中得到探讨,但多项队列研究表明,接受冠状动脉旁路移植术存活的患者在随后的非心脏手术期间风险降低。鉴于两次手术可能会使短期发病率增加,对于非心脏手术前进行冠状动脉血运重建能改善长期生存率的患者,谨慎起见应保留该治疗手段。如果只为这些患者保留冠状动脉血运重建,那么从围手术期和长期心血管护理的角度来看,整体评估应具有成本效益。