骨巨细胞瘤中不包括端粒关联的染色体异常。
Chromosomal anomalies exclusive of telomeric associations in giant cell tumor of bone.
作者信息
McComb E N, Johansson S L, Neff J R, Nelson M, Bridge J A
机构信息
Department of Pathology, University of Nebraska Medical Center, Omaha 68198-5440, USA.
出版信息
Cancer Genet Cytogenet. 1996 Jun;88(2):163-6. doi: 10.1016/0165-4608(95)00362-2.
The occurrence of telomeric associations in giant cell tumor of bone is well recognized. However, there has been little emphasis on clonal structural abnormalities that may be seen in addition to or in the absence of telomeric associations. Two cases of giant cell tumor of bone are presented in this study demonstrating clonal karyotypic anomalies other than telomeric association with a review of previously reported cases showing similar findings.
骨巨细胞瘤中出现端粒联合现象已得到充分认识。然而，除了端粒联合现象或在无端粒联合现象时可能出现的克隆性结构异常却很少受到关注。本研究报告了两例骨巨细胞瘤病例，展示了除端粒联合之外的克隆性核型异常，并回顾了先前报道的显示类似发现的病例。
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