Fabbri L, Mapp C, Rossi A, Cortese S, Saia B
Lav Um. 1977 Mar;29(2):50-7.
Thirty-five subjects employed in a phosphoric acid producing plant were studied by the authors. The investigation included: history, according to the C.E.C.A. questionnaire for chronic bronchitis and emphysema; physical examination, chest X-ray spirometry and lung diffusing capacity for carbon monoxide by the steady state method (DLCOSS). High prevalence of chronic bronchitis (45.7%), obstructive spirometric impairment (37.1%), and decreased values of DlcoSS (31.4%) were detected. Two subjects were found to be affected with p 1/0 and 7 with p 0/1 pneumoconiosis. Such findings were significantly related to the lenght of working activity as well as to dust and gaseous fluoride (hydrofluoric acid, hexafluorosilicic acid and silicon tetrafluoride) exposure.
作者对一家磷酸生产厂的35名员工进行了研究。调查包括:根据慢性支气管炎和肺气肿的C.E.C.A.问卷进行病史询问;体格检查、胸部X光、肺量计检查以及采用稳态法测定一氧化碳肺弥散量(DLCOSS)。结果发现慢性支气管炎的患病率很高(45.7%),肺量计检查显示存在阻塞性损伤(37.1%),DLCOSS值降低(31.4%)。发现2名受试者患有p 1/0期尘肺,7名患有p 0/1期尘肺。这些发现与工作活动时长以及粉尘和气态氟化物(氢氟酸、六氟硅酸和四氟化硅)暴露显著相关。