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[Reversible esophageal dysfunction as a side effect of levodopa].

作者信息

Kellner H, Liegl U, Frank M, Zoller W G

机构信息

Medizinische Poliklinik Klinikum Innenstadt, Ludwigs-Maximilians-Universität, München, Deutschland.

出版信息

Bildgebung. 1996 Mar;63(1):48-50.

PMID:8653009
Abstract

We are reporting the case of a 94-year-old male patient with a 10-year history of Parkinson's disease, who was admitted to our hospital with acute obstruction of esophageal passage. Esophageal obstruction was refractory to endoscopic intervention. However, discontinuation of the pre-existing levodopa medication led to its resolution within hours. While dysphagia is commonly encountered in patients with Parkinson's disease, the observed succession of drug discontinuation and resolution of obstruction in this case suggests an as yet rarely described side effect of levodopa. This potential side effect should be included in the differential diagnosis of dysphagia in Parkinson's disease, especially in the case of older patients, who may exhibit an increased rate of intestinal absorption of levodopa.

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