Konstantinidis N, Konstantinidis G, Ristivojević A, Krstić R, Gebauer E
Centar za hemato-onkologiju, Institut za zdravstvenu zastitu dece i omladine, Medicinski fakultet, Novi Sad.
Med Pregl. 1996;49(5-6):225-7.
Congenital leukemia is a very rare form of acute leukemia and up to now more than 100 well documented cases have been published. Symptoms and signs of the disease may be faintly differentiated and be a differential diagnostic problem for a long period of time in comparison to other common diseases of the newborn. This is a case report on two newborns with congenital leukemia. It was an acute non-lymphoblastic leukemia in the first case, and acute lymphoblastic leukemia in the second. In both cases there were nonspecific manifestations of the disease (no weight gaining, hemorrhagic enterocolitis). In both cases polyhemotherapeutic protocols were performed. In the first case only partial remission occurred and death occurred during the hemathologic recidive of the disease. In the second case, 15 months after the diagnose of congenital leukemia has been established, complete remission is in course.
先天性白血病是一种非常罕见的急性白血病形式，到目前为止，已发表了100多例有充分记录的病例。与新生儿其他常见疾病相比，该疾病的症状和体征可能难以区分，并且在很长一段时间内都是一个鉴别诊断问题。这是一篇关于两名先天性白血病新生儿的病例报告。第一例为急性非淋巴细胞白血病，第二例为急性淋巴细胞白血病。两例均有该疾病的非特异性表现（体重不增加、出血性小肠结肠炎）。两例均采用了多种治疗方案。第一例仅出现部分缓解，并在疾病血液学复发期间死亡。第二例在确诊先天性白血病15个月后，病情正处于完全缓解中。
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