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[接受过外科二尖瓣交界切开术患者的经皮二尖瓣成形术]

[Percutaneous mitral valvuloplasty in patients who have undergone surgical commissurotomy].

作者信息

Tamburino C, Passaniti A, Russo G, Felis S, Greco G, Deste W, Calvi V, Fiore C E, Giuffrida G

机构信息

Instituto di Cardiologia, Università degli Studi, Catania.

出版信息

Cardiologia. 1996 Jan;41(1):41-4.

PMID:8697468
Abstract

Percutaneous mitral valvuloplasty (PMV) was performed with Inoue's catheter, by anterograde approach, in 19 patients (2 males and 17 females, mean age of 56 +/- 13 years) with restenosis after surgical commissurotomy. Mean valvular area increased from 1.2 +/- 0.2 to 1.9 +/- 0.2 cm2 while mean transvalvular gradient decreased from 13 +/- 6 to 7 +/- 4 mmHg. All but 2 patients reached optimal results; one had a suboptimal result (final valvular area > 1.5 cm2, percentage of increase less than 25%), and 1 was sent to the surgeon for a significant increase in mitral regurgitation ( ). At 1 year follow-up, (available for 11 patients), mean valvular area was 1.7 +/- 0.3 cm2 and transmitral gradient was of 5.4 +/- 2 mmHg. Four patients showed a restenosis; 1 of them underwent surgical mitral valve replacement after a second unsuccessful PMV; 2 showed good clinical conditions, while the fourth patient was sent to the surgeon for the high echocardiographic score. At 2-year follow-up, available for 4 patients, the mean gradient was of 5.5 +/- 2.5 mmHg and the mitral valve area was 1.8 +/- 0.2 cm2. NYHA functional class progressively improved after the procedure in all patients but those undergoing mitral valve replacement. In conclusion, despite the occurrence of restenosis, PMV seems to be feasible in patients who already underwent surgical commissurotomy; this procedure can avoid the risks of a second surgery, and should be considered the first choice treatment in these patients.

摘要

采用Inoue球囊导管经顺行途径对19例(2例男性,17例女性,平均年龄56±13岁)外科交界切开术后再狭窄患者实施经皮二尖瓣成形术(PMV)。平均瓣口面积从1.2±0.2cm²增加至1.9±0.2cm²,平均跨瓣压差从13±6mmHg降至7±4mmHg。除2例患者外,其余患者均达到最佳效果;1例效果欠佳(最终瓣口面积>1.5cm²,增加百分比<25%),1例因二尖瓣反流显著增加而转至外科手术( )。在1年随访时(11例患者可进行随访),平均瓣口面积为1.7±0.3cm²,二尖瓣压差为5.4±2mmHg。4例患者出现再狭窄;其中1例在第二次PMV失败后接受了二尖瓣置换手术;2例临床情况良好,而第4例患者因超声心动图评分较高而转至外科手术。在2年随访时(4例患者可进行随访),平均压差为5.5±2.5mmHg,二尖瓣瓣口面积为1.8±0.2cm²。除接受二尖瓣置换手术的患者外,所有患者术后纽约心脏协会(NYHA)心功能分级均逐步改善。总之,尽管发生了再狭窄,但PMV对于已经接受过外科交界切开术的患者似乎是可行的;该手术可避免二次手术的风险,应被视为这些患者的首选治疗方法。

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