Nicolai T, von Mutius E
Universitätskinderklinik München, Dr v Haunersches Kinderspital, Germany.
Toxicol Lett. 1996 Aug;86(2-3):105-13. doi: 10.1016/0378-4274(96)03681-8.
We assessed the prevalence of asthma and allergic disorders in 9-11 year old children in Leipzig and Halle in East Germany, and Munich, West Germany. Both East German cities were heavily polluted due to private coal burning and industrial emissions, whereas Munich has moderate industry but heavy car traffic. All fourth grade pupils in Munich (n = 7445) were compared with those in Leipzig, 1990 (n = 1429) and Leipzig and Halle, 1991 (n = 3105). The prevalence of hay fever and skin test reactivity to common aeroallergens was considerably higher in West Germany as compared to East Germany. Furthermore, the prevalence of asthma was also higher in the West German study area. However, when atopy was taken into account, there was no longer a significant difference in the prevalence of asthma between the two parts of the country.
我们评估了德国东部莱比锡和哈雷以及德国西部慕尼黑9至11岁儿童的哮喘和过敏性疾病患病率。东德的这两个城市因私人燃煤和工业排放而污染严重,而慕尼黑工业规模适中,但汽车交通繁忙。将慕尼黑所有四年级学生(n = 7445)与1990年莱比锡的学生(n = 1429)以及1991年莱比锡和哈雷的学生(n = 3105)进行了比较。与东德相比,西德的花粉热患病率以及对常见气传变应原的皮肤试验反应性要高得多。此外,西德研究区域的哮喘患病率也更高。然而,若考虑特应性,该国两部分地区哮喘患病率不再存在显著差异。