Anderson J M
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06510-8024, USA.
Curr Biol. 1996 Apr 1;6(4):382-4. doi: 10.1016/s0960-9822(02)00501-8.
Diverse extracellular signals are coupled at the plasma membrane to intracellular signal transduction pathways and the cytoskeleton. Members of a ubiquitous multidomain family of proteins, the MAGUK proteins, are emerging as common mediators of this coupling.
多种细胞外信号在质膜处与细胞内信号转导途径和细胞骨架相偶联。一类普遍存在的多结构域蛋白家族成员,即膜相关鸟苷酸激酶(MAGUK)蛋白,正逐渐成为这种偶联的常见介质。