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后尿道瓣膜症男孩的长期膀胱功能障碍

Long-term bladder dysfunction in boys with posterior urethral valves.

作者信息

Pfister C, Wagner L, Dacher J N, Liard A, Boillot B, Mitrofanoff P

机构信息

Clinique Chirurgicale Infantile, C.H.U. Charles Nicolle, Rouen, France.

出版信息

Eur J Pediatr Surg. 1996 Aug;6(4):222-4. doi: 10.1055/s-2008-1066512.

Abstract

We report a series of 60 children operated on for posterior urethral valve (PUV) before the age of 5 years and followed up for 10 years. This work aims to study the vesico-sphincteric sequelae of this malformation. 38 patients showed early urinary incontinence post-operatively. Of them, 20 were re-evaluated 10 years later by pelvic ultrasonography, pressure flow studies combined with EMG and assessment of renal function. 8 patients refused to undergo these investigations and 10 were lost to follow-up. Of the 28 evaluable patients, 22 are currently continent and a complete urodynamic study was performed for the 6 (10%) incontinent patients. Of them, 3 showed uninhibited detrusor contractions. The vesical compliance was frequently within the normal limits. No case of detrusor-sphincteric dyssynergy or urethral hypotony was found. 2 were successfully treated by oxybutinin and biofeedback reeducation, 2 were partially improved but their prostates are still in growth and the possibility of implanting an artificial sphincter was discussed in the remaining 2. The urodynamic evaluation of those patients in the long-term is encouraging.

摘要

我们报告了一组60例5岁前接受后尿道瓣膜(PUV)手术并随访10年的儿童。这项工作旨在研究这种畸形的膀胱括约肌后遗症。38例患者术后早期出现尿失禁。其中,20例在10年后通过盆腔超声、压力流研究结合肌电图以及肾功能评估进行了重新评估。8例患者拒绝接受这些检查,10例失访。在28例可评估的患者中,22例目前已能自主控制排尿,对6例(10%)仍有尿失禁的患者进行了完整的尿动力学研究。其中,3例显示逼尿肌无抑制性收缩。膀胱顺应性通常在正常范围内。未发现逼尿肌括约肌协同失调或尿道张力过低的病例。2例通过奥昔布宁和生物反馈再教育成功治疗,2例部分改善,但他们的前列腺仍在生长,对其余2例讨论了植入人工括约肌的可能性。对这些患者的长期尿动力学评估结果令人鼓舞。

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