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[支气管黏液表皮样癌:附3例报告]

[Bronchial mucoepidermoid carcinoma: apropos of 3 cases].

作者信息

Deschildre A, Sardet A, Brouard J, Delaisi B, Boussard L, Boccon-Gibod L, Gosselin B, Tournier G, Leclerc F

机构信息

Service de réanimation infantile, CHU de Lille, France.

出版信息

Arch Pediatr. 1996 Jul;3(7):689-93. doi: 10.1016/0929-693x(96)87091-6.

Abstract

BACKGROUND

Mucoepidermoïd carcinomas (MEC) are very rare (less than 20 cases reported in the literature) and potentially malignant bronchial gland carcinomas.

PATIENTS

Three children, two boys (11 and 7 years old) and one girl (5 years old) suffered from respiratory symptoms such as cough, recurrent pneumonia and/or hemoptysis for 2 to 12 months. Bronchial endoscopy showed a mass into the left (two cases), or the right main bronchus (one case). Chest CT scan identified local extension, and lung-associated lesions. Histopathological study concluded to MEC in the three cases. The patients were treated by segmental bronchial resection, completed with left upper lobectomy (two cases), bronchotomy (one case). All the tumor could be removed; there was no metastasis. The outcome was uneventful with a 8 to 24 months follow-up.

CONCLUSION

Bronchial tumors of children must be considered in patients with chronic cough, recurrent pneumonia and/or hemoptysis and require bronchial endoscopy for their diagnosis.

摘要

背景

黏液表皮样癌(MEC)非常罕见(文献报道少于20例),是具有潜在恶性的支气管腺癌。

患者

三名儿童,两名男孩(11岁和7岁)和一名女孩(5岁),有咳嗽、反复肺炎和/或咯血等呼吸道症状达2至12个月。支气管镜检查显示肿块位于左主支气管(两例)或右主支气管(一例)。胸部CT扫描确定了局部扩展及肺部相关病变。组织病理学研究在三例中均诊断为黏液表皮样癌。患者接受了节段性支气管切除术,其中两例辅以左上肺叶切除术,一例辅以支气管切开术。所有肿瘤均得以切除;无转移。随访8至24个月,结果平稳。

结论

对于有慢性咳嗽、反复肺炎和/或咯血的患者,必须考虑儿童支气管肿瘤,诊断需要进行支气管镜检查。

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