Lee C Y, Lau K W, Ding Z P, Tan A, Chan C, Koh T H, Quek S, Chee T S, Ng A, Johan A
Department of Cardiology Singapore General Hospital.
Singapore Med J. 1995 Oct;36(5):474-8.
The aim of this study was to determine the safety profile, mitral valve outcome and follow-up functional status after percutaneous balloon mitral valvuloplasty (PBMV) in patients with mitral restenosis post-surgical commissurotomy.
Sixteen patients with symptomatic mitral restenosis after previous surgical commissurotomy underwent valvuloplasty using the Inoue balloon stepwise dilatation method. Echocardiography was performed before and after the procedure to evaluate the mitral valve area.
All procedures were successfully completed without cardiac perforation, thromboembolism, resultant severe mitral regurgitation or death. The mitral valve area improved from 0.9 +/- 0.2 to 1.6 +/- 0.3 (p = 0.0001), accompanied by a significant immediate reduction in the left atrial pressure and transmitral gradient. Compared with PBMV in patients without past mitral surgery, patients with mitral restenosis undergoing PBMV experienced less valve area improvement but the difference was not significant (p = 0.137). Optimal valve enlargement resulting in mild mitral stenosis was achieved in 12 of the 16 patients. Midterm symptomatic benefit was observed in almost all patients.
In view of the excellent success rate, low complication risk, the optimal haemodynamic results and favourable functional outcome afforded by mitral balloon valvuloplasty in patients with mitral restenosis after prior surgical commissurotomy, it is logical that balloon mitral valvuloplasty, where available, should be the initial treatment modality in this group of patients with suitable valve morphology before considering repeat mitral surgery.
本研究旨在确定接受过二尖瓣交界切开术的二尖瓣再狭窄患者经皮二尖瓣球囊成形术(PBMV)后的安全性、二尖瓣结局及随访功能状态。
16例既往接受过二尖瓣交界切开术且有症状性二尖瓣再狭窄的患者采用Inoue球囊逐步扩张法进行瓣膜成形术。术前和术后均行超声心动图检查以评估二尖瓣面积。
所有手术均成功完成,未发生心脏穿孔、血栓栓塞、严重二尖瓣反流或死亡。二尖瓣面积从0.9±0.2改善至1.6±0.3(p = 0.0001),同时左心房压力和跨二尖瓣压差立即显著降低。与未接受过二尖瓣手术的患者行PBMV相比,接受PBMV的二尖瓣再狭窄患者瓣膜面积改善较小,但差异无统计学意义(p = 0.137)。16例患者中有12例实现了最佳瓣膜扩张,导致轻度二尖瓣狭窄。几乎所有患者均观察到中期症状改善。
鉴于二尖瓣球囊成形术在既往接受过二尖瓣交界切开术的二尖瓣再狭窄患者中成功率高、并发症风险低、血流动力学结果最佳且功能结局良好,对于这组瓣膜形态合适的患者,在考虑再次二尖瓣手术之前,若可行,球囊二尖瓣成形术应作为初始治疗方式,这是合理的。