Robinson J S, Thompson J M, Barratt R S
Br J Anaesth. 1977 Aug;49(8):745-54. doi: 10.1093/bja/49.8.745.
All halothane vaporizers tested for leakage when turned off, leaked significant amounts of halothane and this may represent a hazard to patients liable to develop halothane hepatitis or malignant hyperpyrexia. The hazard from leaking vaporizers may be reduced considerably by the use of well-designed bypass units. Circuit contamination by halothane may still result from such sources as neoprene seals around flowmeters, breathing bags and anaesthetic hose which have had previous contact with halothane vapour, whether or not an apparatus is in use. The hazard from contaminated hoses and bags may be reduced considerably by washing and then hanging in a halothane-free atmosphere for a day. The hazard from contamined rubber or plastic components of the anaesthetic machine can be eliminated only by using one apparatus without the vaporizers having been attached at any time during its working life. Similarly, hazards may arise from trichloroethylene vaporizers and from circuit components contaminated with trichloroethylene.
所有经测试的氟烷蒸发器在关闭时都会发生泄漏,泄漏出大量氟烷,这可能对易患氟烷性肝炎或恶性高热的患者构成危害。使用设计良好的旁路装置可大大降低蒸发器泄漏带来的危害。氟烷对回路的污染仍可能源于流量计周围的氯丁橡胶密封件、呼吸袋和曾接触过氟烷蒸汽的麻醉软管等源头,无论设备是否在使用。通过清洗然后挂在无氟烷的环境中一天,可大大降低受污染的软管和袋子带来的危害。麻醉机受污染的橡胶或塑料部件带来的危害只有在设备使用寿命期间从未连接过蒸发器的情况下才能消除。同样,三氯乙烯蒸发器以及被三氯乙烯污染的回路部件也可能产生危害。