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[恶性肿瘤中行保留幽门十二指肠胰头切除术的当前适应证]

[Current indications for pylorus saving duodenopancreatic head resection in malignancy].

作者信息

Reith H B, Kozuschek W, Traverso L W

机构信息

Chirurgische Universitätsklinik Bochum, Knappschaftskrankenhaus.

出版信息

Langenbecks Arch Chir. 1996;381(4):207-11. doi: 10.1007/BF00571686.

Abstract

The Whipple procedure has been improved by preservation of a functioning pylorus. A functioning pylorus is important because marginal ulceration is avoided and, compared to the standard Whipple procedure with gastric resection, more patients can gain weight postoperatively. The most common indications are carcinomas of ampulla of Vater and periampullary tumors. In patients with pancreatic adenocarcinoma the pylorus-preserving variety results in equal or better survival rates. In 56 patients with pylorus preservation, 32 with ductal carcinoma, and 28 with Kausch-Whipple between 1985 and 1993, our results showed slightly better survival rates and better postoperative nutrition. The weakest aspect of the radical resection addresses the retroperitoneal margin of the pancreas head and not the gastric resection.

摘要

保留有功能的幽门改进了惠普尔手术。保留有功能的幽门很重要,因为可避免边缘性溃疡,并且与标准的胃切除惠普尔手术相比,更多患者术后能增加体重。最常见的适应证是壶腹周围癌和壶腹周围肿瘤。对于胰腺腺癌患者,保留幽门的术式能带来相同或更好的生存率。在1985年至1993年间,我们对56例保留幽门的患者、32例导管癌患者和28例行考施-惠普尔手术的患者进行研究,结果显示生存率略高,术后营养状况更好。根治性切除最薄弱的环节在于胰头的腹膜后切缘,而非胃切除。

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