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IgA肾病和过敏性紫癜患者的免疫球蛋白皮肤及肾脏沉积物

[Immunoglobulin skin and renal deposits in patients with IgA nephropathy and Schonlein-Henoch purpura].

作者信息

Szymanik-Grzelak H, Gura C, Kozak-Białasik D, Sulej J, Jarzabek-Chorzelska M, Chadzyńska M, Sieniawska M

机构信息

Katedra i Klinika Pediatrii i Nefrologii Akademii Medycznej w Warszawie.

出版信息

Pediatr Pol. 1996 Apr;71(4):321-5.

PMID:8975219
Abstract

Skin biopsy was performed in 17 of 27 children with IgA nephropathy (IgAN) and 45 of 62 children with Schönlein-Henoch purpura (SHP). Renal biopsy was done in all patients with IgAN and in 51 of 62 with SHP. There was no correlation between presentation of immunological deposits in skin and renal biopsy. Deposits of IgA with or without other deposits or other deposits without IgA were observed in different pathomorphological states. Correlation between IgA serum concentration and presentation of deposits in skin was not observed. Attention was drawn to the high proportion of negative results in skin biopsy.

摘要

对27例IgA肾病(IgAN)患儿中的17例以及62例过敏性紫癜(SHP)患儿中的45例进行了皮肤活检。所有IgAN患者及62例SHP患者中的51例进行了肾活检。皮肤和肾活检中免疫沉积物的表现之间无相关性。在不同的病理形态学状态下观察到有或无其他沉积物的IgA沉积物或无IgA的其他沉积物。未观察到IgA血清浓度与皮肤沉积物表现之间的相关性。请注意皮肤活检中阴性结果的比例较高。

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