Lambregts-van Weezenbeek C S, Keizer S T, Sebek M M, Schepp-Beelen J C, van der Loo C J
Koninklijke Nederlandse Centrale Vereniging tot bestrijding der Tuberculose, Den Haag.
Ned Tijdschr Geneeskd. 1996 Nov 16;140(46):2293-5.
Nosocomial transmission of multiresistant tuberculosis in the Netherlands is described for the first time in this article. It was detected by systematic country-wide DNA-fingerprinting. By the time the contact case (a man aged 35) developed disease he was residing in another part of the country. Contact-investigation by the Municipal Health Services involved revealed that the (HIV negative) contact case had been in contact with the index case (a man aged 27) during hospitalisation two years earlier. An analysis of the infection control measures applied, showed that inadequate treatment, early discharge from isolation and lack of bacteriological control (no sputum conversion documented) led to this hospital transmission.
本文首次描述了荷兰多重耐药结核病的医院内传播情况。它是通过全国系统性的DNA指纹识别检测到的。当接触者病例(一名35岁男性)发病时,他居住在该国的另一个地区。所涉及的市卫生服务机构进行的接触者调查显示,该(HIV阴性)接触者病例在两年前住院期间曾与索引病例(一名27岁男性)有过接触。对所采取的感染控制措施的分析表明,治疗不当、过早解除隔离以及缺乏细菌学监测(未记录痰菌转阴情况)导致了此次医院内传播。