Giese M J
J Am Optom Assoc. 1997 Jan;68(1):50-4.
Corneal distortion in contact lens wear can be produced by epithelial wrinkles, compression rings, and anterior corneal surface mosaic. True corneal wrinkling can also occur but is an extremely rare phenomenon. These conditions can be manifested as alterations in keratometry and corneal topography.
A case report is presented of a 17-year-old patient with Marfan syndrome. Central corneal wrinkling developed in his right eye while he was wearing low-water-content hydrogel contact lenses. No visual discomfort or distortions were noted.
The patient was refitted with a non-HEMA hydrogel polymer contact lens, with no further episodes of corneal wrinkling observed during subsequent care of the patient.
This case represents an example of corneal wrinkling in a patient wearing hydrogel contact lenses. It is unlikely this finding is related to Marfan syndrome.
佩戴隐形眼镜时角膜变形可由上皮皱纹、压迫环和角膜前表面镶嵌引起。真正的角膜起皱也可能发生，但极为罕见。这些情况可表现为角膜曲率计和角膜地形图的改变。
报告1例17岁马凡综合征患者。其右眼在佩戴低含水量水凝胶隐形眼镜时出现中央角膜起皱。未发现视觉不适或变形。
为该患者重新配戴非甲基丙烯酸羟乙酯水凝胶聚合物隐形眼镜，在后续护理中未观察到角膜起皱的进一步发作。
本病例是佩戴水凝胶隐形眼镜患者角膜起皱的一个例子。这一发现不太可能与马凡综合征有关。
