Henschke U K, Luande G J, Choppala J D
J Natl Med Assoc. 1977 Aug;69(8):581-4.
Distant metastases are the principal cause of death from cancer. Many animal experiments in the last 25 years have shown consistently that distant metastases can be significantly reduced by anticoagulants and fibrinolytic agents. Since aspirin inhibits platelet function and increases fibrinolytic activity in humans, it may be effective in preventing metastases in cancer patients. It is suggested that aspirin be offered as an option to cancer patients who are at risk for distant metastases.
远处转移是癌症致死的主要原因。过去25年里的许多动物实验始终表明,抗凝剂和纤溶药物能够显著减少远处转移。由于阿司匹林可抑制人体血小板功能并增强纤溶活性,因此它可能对预防癌症患者发生转移有效。建议将阿司匹林作为有远处转移风险的癌症患者的一种选择。