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婴幼儿结膜炎

Conjunctivitis in infants and children.

作者信息

Wald E R

机构信息

Children's Hospital of Pittsburgh, PA, USA.

出版信息

Pediatr Infect Dis J. 1997 Feb;16(2 Suppl):S17-20. doi: 10.1097/00006454-199702001-00005.

Abstract

BACKGROUND

Acute bacterial conjunctivitis, chiefly affecting young children, is generally caused by one of three common pathogens, Haemophilus influenzae, Streptococcus pneumoniae and adenovirus. H. influenzae is the most prevalent causative organism. Some patients presenting initially with conjunctivitis subsequently develop acute otitis media, with H. influenzae the most common etiologic agent of what has been termed the "conjunctivitis-otitis" syndrome. Optimal treatment of acute conjunctivitis would result in a clinical and bacteriologic cure of the conjunctivitis and the prevention of the development of otitis media. Application of topical antimicrobials at 4- to 6-h intervals a day for 1 week to 10 days results in the resolution of the conjunctivitis. However, topical treatment is difficult to administer to toddlers and does not effectively reduce the potential for the development of otitis media. Compared with topical and placebo treatment, oral antibiotics effective against H. influenzae have proved to be most effective in preventing the otitis media associated with conjunctivitis.

CONCLUSION

Acute bacterial conjunctivitis is a common disorder in children < 6 years of age. H. influenzae is the most common etiology of the "conjunctivitis-otitis syndrome." The optimal treatment for this condition is still being studied.

摘要

背景

急性细菌性结膜炎主要影响幼儿,通常由三种常见病原体之一引起,即流感嗜血杆菌、肺炎链球菌和腺病毒。流感嗜血杆菌是最常见的致病微生物。一些最初表现为结膜炎的患者随后会发展为急性中耳炎,流感嗜血杆菌是所谓“结膜炎-中耳炎”综合征最常见的病因。急性结膜炎的最佳治疗方法应能实现结膜炎的临床和细菌学治愈,并预防中耳炎的发生。每天每隔4至6小时局部应用抗菌药物,持续1周 至10天可使结膜炎消退。然而,局部治疗对幼儿难以实施,且不能有效降低发生中耳炎的可能性。与局部治疗和安慰剂治疗相比,对流感嗜血杆菌有效的口服抗生素已被证明在预防与结膜炎相关的中耳炎方面最为有效。

结论

急性细菌性结膜炎在6岁以下儿童中是一种常见疾病。流感嗜血杆菌是“结膜炎-中耳炎综合征”最常见的病因。针对这种情况的最佳治疗方法仍在研究中。

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