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[永久性及短期和中期临时性腔静脉滤器的使用标准及适应证。个人经验及文献综述]

[Criteria for utilization and indications for use of permanent and short- and medium term temporary endocaval filters. Personal experience and review of the literature].

作者信息

Fuochi C, Furlan F, Pellegrini M, Moser E, Dalla Palma F

出版信息

Radiol Med. 1996 Oct;92(4):431-7.

PMID:9045246
Abstract

Screening and prophylaxis of the population at risk is the most correct approach to thromboembolic disease. Caval filters play a major role in the prevention of pulmonary embolism, but their use remains widely controversial, even if they are an alternative or additional method to medical therapy and not antithetical to it. July, 1990, to September, 1995, seventy-seven permanent vena cava filters (59 LGM, 13 Filcard and 5 titanium-Greenfield), 22 short-duration temporary vena cava filters (11 LGT, 6 Filcard, 3 Filcard-Emanuelli and 2 Lysofilter) and 10 mid-duration temporary vena cava filters (Tempofilter) were inserted in 109 patients (55 men and 54 women) aged 17-88 years. An inferior vena cavogram was always made before filter insertion to "map" the inferior vena cava and its tributaries (renal veins) and to assess caval size. This is a mandatory step to exclude or confirm the presence of endocaval thrombi. Sixty-eight filters were inserted percutaneously via a right internal transjugular approach, 40 via a common transfemoral approach (34 right and 6 left) using the same route as inferior cavography and digital pneumoangiography. One temporary filter was inserted via a right transhumeral approach. Sixty-three patients (57.8%) (44 with a permanent filter, 14 with a temporary filter and 5 with a Tempofilter) had medical diseases, 7 patients (6.4%) (4 with a permanent filter, one with a temporary filter and 2 with a Tempofilter) had surgical conditions; 10 patients (9.2%) (7 with a permanent filter and 3 with a Tempofilter) were surgical-orthopedic patients. Twenty-seven patients (24.8%) (22 with a permanent and 5 with a temporary filter) had cancer. Two patients (1.8%) with a temporary filter were breast feeding. All the patients had deep venous thrombosis of the lower limbs, including the inferior vena cava and the right renal vein in two patients. A proximal floating thrombus and a pulmonary thromboembolism was diagnosed in 41 (37.6%) and 34 (31.2%) cases, respectively. The temporary filters remained in situ 1-4 days and the Tempofilters 3-5 weeks. A pelvic hematoma developed (because of heparin?) after the insertion of a temporary filter and a Tempofilter branch detached and migrated into a lower branch of the left pulmonary artery were reported as immediate and short-term consequences. There were no early or late consequences for the patients. An axillary hemorrhage was observed in the site of previous surgery, during fibrinolysis with a Lysofilter, as well as the incomplete opening of a titanium-Greenfield filter and of two permanent LGM filters, partly trapped within endocaval thrombi. No further consequences to the patients due to permanent filters were observed, nor any case of symptomatic pulmonary thromboembolism, in patients with permanent or temporary filters. With reference to the relative literature and to their own experience, the Authors propose a detailed and rational synthesis of the diagnostic-instrumental approach protocol to thromboembolic disease.

摘要

对高危人群进行筛查和预防是应对血栓栓塞性疾病最正确的方法。下腔静脉滤器在预防肺栓塞方面发挥着重要作用,但其应用仍存在广泛争议,即便它是药物治疗的一种替代或辅助方法,而非与之相悖。1990年7月至1995年9月,109例年龄在17至88岁的患者(55名男性和54名女性)植入了77个永久性腔静脉滤器(59个LGM,13个Filcard和5个钛制格林菲尔德滤器)、22个短期临时性腔静脉滤器(11个LGT,6个Filcard,3个Filcard - Emanuelli和2个Lysofilter)以及10个中期临时性腔静脉滤器(Tempofilter)。在植入滤器前总会进行下腔静脉造影,以“描绘”下腔静脉及其分支(肾静脉)并评估腔静脉大小。这是排除或确认腔内血栓存在的必要步骤。68个滤器通过右颈内静脉经皮穿刺途径植入,40个通过与下腔静脉造影及数字气血管造影相同的经股总途径(34个右侧和6个左侧)植入。1个临时性滤器通过右肱动脉途径植入。63例患者(57.8%)(44例植入永久性滤器,14例植入临时性滤器,5例植入Tempofilter)患有内科疾病,7例患者(6.4%)(4例植入永久性滤器,1例植入临时性滤器,2例植入Tempofilter)患有外科疾病;10例患者(9.2%)(7例植入永久性滤器,3例植入Tempofilter)为外科骨科患者。27例患者(24.8%)(22例植入永久性滤器,5例植入临时性滤器)患有癌症。2例植入临时性滤器的患者正在哺乳期。所有患者均有下肢深静脉血栓形成,其中2例患者还累及下腔静脉及右肾静脉。分别在41例(37.6%)和34例(31.2%)病例中诊断出近端漂浮血栓和肺血栓栓塞。临时性滤器留置1至4天,Tempofilter留置3至5周。报告了植入临时性滤器和Tempofilter后出现盆腔血肿(因肝素?)以及Tempofilter分支分离并迁移至左肺动脉下支等即刻和短期后果。对患者未造成早期或晚期影响。在使用Lysofilter进行纤溶治疗期间,在既往手术部位观察到腋窝出血,以及钛制格林菲尔德滤器和两个永久性LGM滤器未完全打开,部分被困于腔内血栓中。未观察到永久性滤器对患者造成进一步影响,植入永久性或临时性滤器的患者也未出现有症状的肺血栓栓塞病例。参考相关文献及自身经验,作者提出了针对血栓栓塞性疾病的诊断 - 器械方法方案的详细且合理的综合内容。

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