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小儿患者使用艾哈迈德青光眼引流阀植入物的初步临床经验。

Initial clinical experience with the Ahmed Glaucoma Valve implant in pediatric patients.

作者信息

Coleman A L, Smyth R J, Wilson M R, Tam M

机构信息

Jules Stein Eye Institute, UCLA School of Medicine, USA.

出版信息

Arch Ophthalmol. 1997 Feb;115(2):186-91. doi: 10.1001/archopht.1997.01100150188007.

Abstract

OBJECTIVE

To evaluate the Ahmed Glaucoma Valve implant, an aqueous shunting device with a unidirectional valve mechanism, in patients younger than 18 years.

DESIGN

Prospective case series.

SETTING

Tertiary care hospital.

PATIENTS

Twenty-one consecutive patients younger than 18 years. The median age of patients was 4.8 years (range, 0.23-17.9 years)

INTERVENTION

Placement of an Ahmed Glaucoma Valve implant between April 1992 and April 1994.

MAIN OUTCOME MEASURE

Time after surgery without failure. Success was defined as an average intraocular pressure less than 22 mm Hg for the last 2 follow-ups in eyes with preoperative intraocular pressure greater than 22 mm Hg, or an intraocular pressure that was lowered by at least 20% from preoperative values in eyes with preoperative intraocular pressure less than 22 mm Hg, and no additional glaucoma surgeries or visually devastating complications.

RESULTS

Cumulative probabilities of success at 12 and 24 months were 77.9% +/- 8.8% and 60.6% +/- 13.7%, respectively. One eye had a flat anterior chamber and suprachoroidal hemorrhage on the first postoperative day. No other eyes had flat or shallow anterior chambers that required reformation. In 3 eyes the implant extruded from underneath the conjunctiva and was removed. In 2 other eyes the average intraocular pressure for the last 2 follow-ups was greater than 22 mm Hg. In 1 eye with an intraocular pressure less than 22 mm Hg preoperatively, the intraocular pressure was not reduced by at least 20%, although the number of antiglaucoma medications was reduced.

CONCLUSION

The 12-and 24-month success rates of the Ahmed Glaucoma Valve implant are similar to those of other implants when used in a pediatric population.

摘要

目的

评估艾哈迈德青光眼引流阀植入物(一种带有单向瓣膜机制的房水引流装置)在18岁以下患者中的应用情况。

设计

前瞻性病例系列研究。

地点

三级医疗中心。

患者

21例连续的18岁以下患者。患者的中位年龄为4.8岁(范围:0.23 - 17.9岁)。

干预措施

1992年4月至1994年4月期间植入艾哈迈德青光眼引流阀。

主要观察指标

术后无失败的时间。成功的定义为:术前眼压高于22 mmHg的眼睛,在最后2次随访中平均眼压低于22 mmHg;或术前眼压低于22 mmHg的眼睛,眼压较术前值降低至少20%,且无额外的青光眼手术或导致视力严重受损的并发症。

结果

12个月和24个月时成功的累积概率分别为77.9%±8.8%和60.6%±13.7%。1只眼睛在术后第1天出现无前房和脉络膜上腔出血。没有其他眼睛出现需要重新形成的扁平或浅前房。3只眼睛的植入物从结膜下挤出并被取出。另外2只眼睛在最后2次随访中的平均眼压高于22 mmHg。1只术前眼压低于22 mmHg的眼睛,尽管抗青光眼药物数量减少,但眼压未降低至少20%。

结论

在儿科患者中使用时,艾哈迈德青光眼引流阀植入物的12个月和24个月成功率与其他植入物相似。

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