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细针穿刺细胞学检查在骨肿瘤诊断中的应用

Fine needle aspiration cytology in the diagnosis of bone tumours.

作者信息

Jayaram G, Gupta M

机构信息

Department of Pathology, Maulana Azad Medical College and Associated Lok Nayak Jai Prakash Narain Hospital, New Delhi, India.

出版信息

Malays J Pathol. 1994 Dec;16(2):137-44.

PMID:9053562
Abstract

Fine needle aspiration (FNA) cytology was performed on 62 primary and 22 metastatic bone tumours. Histological correlation was available in all 62 primary bone tumours, which included 7 benign and 53 malignant tumours. The most common of the malignant tumours were Ewing's sarcoma, followed by giant cell tumour, osteosarcoma and chondrosarcoma. The benign tumours included 4 enchondromas, 1 chondromyxoid fibroma and 2 osteochondromas. The overall cytodiagnostic accuracy in primary malignant bone tumours was 86.9%, the specificity was 100% and cytological categorization of tumours was possible in the majority of cases. This eliminated the need for bioptic confirmation. Our results indicate that FNA cytology is a valuable diagnostic tool in bone tumours.

摘要

对62例原发性骨肿瘤和22例转移性骨肿瘤进行了细针穿刺(FNA)细胞学检查。所有62例原发性骨肿瘤均有组织学对照,其中包括7例良性肿瘤和53例恶性肿瘤。最常见的恶性肿瘤是尤因肉瘤,其次是巨细胞瘤、骨肉瘤和软骨肉瘤。良性肿瘤包括4例内生软骨瘤、1例软骨黏液样纤维瘤和2例骨软骨瘤。原发性恶性骨肿瘤的总体细胞诊断准确率为86.9%,特异性为100%,大多数病例能够对肿瘤进行细胞学分类。这消除了活检确认的必要性。我们的结果表明,FNA细胞学是骨肿瘤诊断的一种有价值的工具。

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