Byrnes G A, Leen M M, Wong T P, Benson W E
Department of Ophthalmology, National Naval Medical Center, Bethesda, MD 20889-5000, USA.
Ophthalmology. 1995 Sep;102(9):1308-11. doi: 10.1016/s0161-6420(95)30870-6.
Ciliary block (malignant) glaucoma is a rare surgical complication occurring in patients with pre-existing glaucoma. Misdirected aqueous fluid causes forward movement of the lens/iris diaphragm, shallowing the central and peripheral anterior chamber. Although most patients with ciliary block respond to medical or laser therapy, those with refractory glaucoma often require pars plana vitrectomy to normalize aqueous flow.
The medical records of 21 consecutive patients with refractory ciliary block glaucoma treated by pars plana vitrectomy were reviewed retrospectively to determine the efficacy of this procedure in alleviating ciliary block. Data were collected regarding anatomic characteristics of the eye, history of glaucoma, prior ocular surgery, and outcome after vitrectomy.
Pre-existing glaucoma and recent intraocular surgery were noted in all patients with ciliary block glaucoma. Of 21 eyes, 8 (38%) had undergone multiple prior intraocular surgeries. The initial pars plana vitrectomy was successful in alleviating ciliary block in 14 (70%) of 20 eyes. Of those six eyes that failed to improve after initial vitrectomy, five (83%) were phakic. Additional vitrectomy surgery to relieve ciliary block was required in three (60%) of five phakic patients who failed initial vitrectomy. Complications during the treatment of ciliary block included cataract formation, retinal detachment, bleb failure, and serous choroidal detachment.
Pars plana vitrectomy is a useful adjunct to therapy for ciliary block glaucoma when medical and laser treatment fail to alleviate the process. Surgically removing the anterior hyaloid to re-establish normal aqueous flow constitutes the primary goal of surgery. In some cases, surgery is compromised by poor visualization of the anterior hyaloid, avoiding glaucoma filtration sites, and guarding against damage to the crystalline lens.
睫状环阻滞(恶性)青光眼是一种发生于已有青光眼患者的罕见手术并发症。房水引流异常导致晶状体/虹膜隔向前移位,使中央和周边前房变浅。尽管大多数睫状环阻滞患者对药物或激光治疗有反应,但那些难治性青光眼患者通常需要行玻璃体切割术以恢复房水正常引流。
回顾性分析连续21例行玻璃体切割术治疗的难治性睫状环阻滞性青光眼患者的病历,以确定该手术缓解睫状环阻滞的疗效。收集有关眼部解剖特征、青光眼病史、既往眼部手术史以及玻璃体切割术后结果的数据。
所有睫状环阻滞性青光眼患者均有既往青光眼病史和近期眼部手术史。21只眼中,8只(38%)曾接受过多次既往眼部手术。最初的玻璃体切割术使20只眼中的14只(70%)成功缓解了睫状环阻滞。在最初玻璃体切割术后未改善的6只眼中,5只(83%)为有晶状体眼。5只初次玻璃体切割术失败的有晶状体眼患者中,3只(60%)需要再次行玻璃体切割术以缓解睫状环阻滞。睫状环阻滞治疗期间的并发症包括白内障形成、视网膜脱离、滤过泡失败和浆液性脉络膜脱离。
当药物和激光治疗无法缓解病情时,玻璃体切割术是治疗睫状环阻滞性青光眼的有效辅助手段。手术切除前玻璃体膜以恢复正常房水引流是手术的主要目标。在某些情况下,手术会因前玻璃体膜可视化不佳、避开青光眼滤过部位以及防止晶状体损伤而受到影响。