Urban J
Katedra i Klinika Chirurgii Urazowej i Chirurgii Reki Akademii Medycznej we Wrocławiu.
Polim Med. 1996;26(3-4):7-19.
In the last ten years hundreds of alloplastic prostheses of cruciate ligaments of knee (ACL) have been implanted. The remote results after surgeries of this kind were univocally bad. All the known synthetic fibres undergo the process of aging and of constant decrease of their mechanical properties. Research of graft fulfilling the conditions of resistance ACL and investigations over the ways of delaying its degradation are continued. The author investigated 5 kinds of polyester prostheses ACL made of homogeneous polyester fibres with the same mechanical properties only with different texture. To estimate biocompatibility he implanted them to piglets weighing 20-30 kg and to rabbits into dorsum muscles in the place of the cut out ACL. After 3 and 6 months a section of the piglets was made estimating the macroscopic, histological and radiological picture. For the rabbits a section was made after 14 days and 3 months. The investigations confirmed a high biocompatibility of the grafts. Large differences in hypertrophy of particular grafts with fibrous tissue were noticed.
在过去十年中,已经植入了数百个膝关节交叉韧带(前交叉韧带,ACL)的异体人工假体。这类手术的远期效果一直很差。所有已知的合成纤维都会经历老化过程,其机械性能也会持续下降。对满足ACL阻力条件的移植物的研究以及延缓其降解方法的研究仍在继续。作者研究了5种由具有相同机械性能但质地不同的均质聚酯纤维制成的聚酯ACL假体。为了评估生物相容性,他将它们植入体重20 - 30千克的仔猪以及兔子背部肌肉中切除ACL的部位。3个月和6个月后,对仔猪进行切片,评估宏观、组织学和放射学图像。对于兔子,在14天和3个月后进行切片。研究证实了移植物具有高度生物相容性。注意到不同移植物与纤维组织肥大程度存在很大差异。