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[食物过敏的营养不良儿童中针对吸入性变应原的特异性IgE]

[Specific IgE against inhaled allergens in dystreptic children with food allergy].

作者信息

Bujniewicz E, Woś H, Krauze M

机构信息

II Katedry i Kliniki Pediatrii SI. AM. w Katowicach.

出版信息

Pol Merkur Lekarski. 1996 Jul;1(1):28-9.

PMID:9156886
Abstract

Immunoglobulin E specific for the selected inhalator allergens have been determined in 42 children with food allergy and failure to thrive, using tests and equipment 3M (Bio Whittaker). Co-existence of food allergy with hypersensitivity to inhaled allergens have been confirmed in 41 children (41%). An equivalent expression grade of IgE antibodies against food and inhaled antigens has usually been noted. Specific IgE produced in response to house dust and mixed feathers have been seen most frequently, and the first have been found in 37% of the tested children in the concentration exceeding 1.0 Ul/ml (2nd, 3rd and 4th class). The obtained results confirmed that specific IgE antibodies against inhaled allergens are being present in children who fail to grow and suffer from the food allergy. These findings should advocate further investigations in specific IgE antibodies to other groups of allergens.

摘要

利用3M(生物惠特克)公司的检测方法和设备,对42名患有食物过敏且发育不良的儿童测定了针对所选吸入性变应原的免疫球蛋白E。41名儿童(41%)被证实存在食物过敏与吸入性变应原超敏反应共存的情况。通常可观察到针对食物和吸入性抗原的IgE抗体表达水平相当。针对屋尘和混合羽毛产生的特异性IgE最为常见,在37%的受试儿童中发现第一种变应原的浓度超过1.0 Ul/ml(2级、3级和4级)。所得结果证实,生长发育不良且患有食物过敏的儿童体内存在针对吸入性变应原的特异性IgE抗体。这些发现应促使对其他变应原组的特异性IgE抗体展开进一步研究。

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