同步性舌颗粒细胞瘤与鳞状细胞癌。病例报告及文献复习。
Synchronous lingual granular cell tumor and squamous carcinoma. A case report and review of the literature.
作者信息
Said-al-Naief N, Brandwein M, Lawson W, Gordon R, Lumerman H
机构信息
Department of Pathology, Mount Sinai School of Medicine, City University of New York, NY, USA.
出版信息
Arch Otolaryngol Head Neck Surg. 1997 May;123(5):543-7. doi: 10.1001/archotol.1997.01900050099013.
Granular cell tumor (GCT) is a benign lesion with a preference for subcutaneous sites. Marked pseudoepitheliomatous hyperplasia, seen in 10% of GCTs, might be misdiagnosed as squamous cell carcinoma (SCC), and GCT in the oral tissues has been referred to as a medical curiosity in the literature. We report the clinicopathologic, immunohistochemical, and ultrastructural findings in a case of coexistent SCC and GCT in the tongue. There is no evidence in this case that suggests malignant transition of the GCT to carcinoma. To the best of our knowledge, this is the first report of synchronous GCT and SCC in the oral cavity.
颗粒细胞瘤（GCT）是一种好发于皮下部位的良性病变。10%的GCT可见显著的假上皮瘤样增生，可能会被误诊为鳞状细胞癌（SCC），口腔组织中的GCT在文献中被称为医学上的罕见病例。我们报告了一例舌部同时存在SCC和GCT的临床病理、免疫组化及超微结构 findings。该病例中没有证据表明GCT向癌发生了恶性转化。据我们所知，这是口腔内同步发生GCT和SCC的首例报告。
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