Démonet J F
INSERM U 230, Hôpital Purpan, Toulouse, France.
Brain Lang. 1997 Jul;58(3):410-7; discussion 436-58. doi: 10.1006/brln.1997.1806.
Many aspects of subcortical aphasias are not accounted for by a unique pathophysiological mechanism; rather the diversity of the observed symptoms suggests that many functional ensembles, more or less related, to language functions may be disturbed by subcortical lesions. However, such disorders are only moderate in intensity and subcortical aphasias certainly constitute an interesting model for studying the dynamics of recovery of language functions and related neural systems, combining neurolinguistic concepts with advanced functional imaging techniques.
皮质下失语症的许多方面无法用单一的病理生理机制来解释;相反,观察到的症状的多样性表明,许多或多或少与语言功能相关的功能组合可能会受到皮质下病变的干扰。然而,此类障碍的严重程度仅为中度,皮质下失语症无疑构成了一个有趣的模型,可用于结合神经语言学概念与先进的功能成像技术来研究语言功能及相关神经系统的恢复动态。