Goldfarb C R, Colp C, Ongseng F, Finestone H, Havas J
Adult Primary Care Center, Beth Israel Medical Center, New York, New York 10003, USA.
Clin Nucl Med. 1997 Jul;22(7):470-4. doi: 10.1097/00003072-199707000-00005.
To evaluate the findings and usefulness of Ga-67 scanning in recent cases of tuberculosis (TB).
The authors reviewed chest x-ray films and Ga-67 citrate scans of 52 patients with culture-confirmed infection caused by Mycobacterium tuberculosis treated after 1988.
Ga-67 scans were positive in every case, delineating upper lobe lung lesions in 6 patients, diffuse involvement or lower lobe disease in 34 patients, and intrathoracic adenopathy in 15 patients. Pulmonary parenchymal lesions were not detected on x-ray films in 3 patients, and nodal lesions were not apparent in 3 patients. In addition, in 6 patients cervical adenopathy was detected by Ga-67 scintigraphy; 4 underwent biopsy with culture confirmation.
Ga-67 scanning is more sensitive than routine chest radiography for detection of both TB parenchymal lung involvement and adenopathy. Ga-67 imaging facilitates the choice of biopsy sites by identifying accessible peripheral nodes. Typical patterns in recent cases of TB differ significantly from the upper lobe predilection of classical TB.
评估镓-67扫描在近期结核病(TB)病例中的表现及实用性。
作者回顾了1988年后接受治疗的52例经培养确诊为结核分枝杆菌感染患者的胸部X光片和枸橼酸镓扫描结果。
镓-67扫描在所有病例中均为阳性,其中6例显示上叶肺部病变,34例为弥漫性累及或下叶疾病,15例为胸内淋巴结病变。3例患者的肺部实质病变在X光片上未被检测到,3例患者的淋巴结病变不明显。此外,6例患者通过镓-67闪烁扫描检测到颈部淋巴结病变;4例接受活检并经培养证实。
镓-67扫描在检测结核肺部实质受累和淋巴结病变方面比常规胸部X光检查更敏感。镓-67成像通过识别可触及的外周淋巴结来辅助活检部位的选择。近期结核病病例的典型模式与经典结核病以上叶为主的情况有显著差异。