Bollen P, Ellegaard L
Pharmacol Toxicol. 1997;80 Suppl 2:3-4. doi: 10.1111/j.1600-0773.1997.tb01980.x.
Pigs traditionally are used in surgical and physiological research. Since the development of the Minnesota minipig in 1949 at the Hormel Institute (USA), miniature pigs have been introduced as a model in pharmacology and toxicology, because of scientific, economic and ethical reasons.