Patel M, Banerjee B, Block J G, Marshall J B
Division of Gastroenterology, University of Missouri Health Sciences Center, and Harry S. Truman VA Memorial Hospital, Columbia 65212, USA.
Am J Gastroenterol. 1997 Aug;92(8):1368-71.
Patients with Crohn's disease are at increased risk for developing adenocarcinoma of the small bowel and colon. Although several cases of gastric malignancy have been reported in patients with Crohn's disease, the association remains controversial, particularly because most patients have not had gastric Crohn's involvement. We report a patient with long-standing Crohn's disease, with gastric involvement, who developed adenocarcinoma of the gastric outlet. We discuss the association and include a review of the literature.
克罗恩病患者发生小肠和结肠癌的风险增加。虽然已有数例克罗恩病患者发生胃恶性肿瘤的报道,但这种关联仍存在争议,尤其是因为大多数患者并无胃克罗恩病累及。我们报告1例有长期克罗恩病且累及胃的患者,该患者发生了胃出口腺癌。我们讨论了这种关联并对文献进行了综述。