高分辨率磁共振成像技术在颞叶内侧硬化症诊断中的应用。磁共振成像与病理特征的相关性

High resolution MR technique in the diagnosis of mesial temporal sclerosis. Correlative MRI and pathological features.

作者信息

Wasenko J J, Gharagozloo A M, Smith M V, Thomas D

机构信息

Department of Diagnostic Radiology, State University of New York, Health Science Center, Syracuse 13210, USA.

出版信息

Clin Imaging. 1997 Sep-Oct;21(5):319-22. doi: 10.1016/s0899-7071(96)00089-7.

DOI:10.1016/s0899-7071(96)00089-7

PMID:9316749

Abstract

Mesial temporal sclerosis, otherwise known as hippocampal sclerosis, is the most common entity associated with medically intractable temporal lobe epilepsy. The neuronal loss and gliosis of the hippocampus that is pathologically characteristic of this disorder is thought to serve as an epileptogenic substrate. Accurate identification and localization of this pathology is crucial before surgery is considered to potentially cure medically intractable seizures. Magnetic resonance imaging plays a central role in the presurgical work-up. We present a 44-year-old man with a history of intractable partial complex seizures secondary to right-sided mesial temporal sclerosis and discuss the magnetic resonance imaging findings utilizing a high resolution technique.

摘要

内侧颞叶硬化，又称海马硬化，是与药物难治性颞叶癫痫相关的最常见病症。这种疾病的病理特征是海马体的神经元丢失和胶质增生，被认为是致痫灶。在考虑通过手术潜在治愈药物难治性癫痫发作之前，准确识别和定位这种病理状况至关重要。磁共振成像在术前评估中起着核心作用。我们报告一名44岁男性，有右侧内侧颞叶硬化继发难治性部分性复杂发作病史，并利用高分辨率技术讨论磁共振成像结果。