Boone L R, Brown A
J Gen Virol. 1976 May;31(2):261-3. doi: 10.1099/0022-1317-31-2-261.
We have selected two similar variants of Sindbis HR virus which are lethal for mice. Consecutive brain to brain passage series were conducted in suckling and weanling mice. Specific anti-Sindbis HR neutralization tests and protection tests demonstrate that these viruses are derived from the parent Sindbis HR.