[Extemporaneous production of gas standard for the determination of carbon monoxide, hydrogen cyanide and ethylene oxide].

This paper describes a new calibration method for headspace chromatographic assay of carbon monoxide, hydrogen cyanide and ethylene oxide. The calibration method is based on the in situ formation of gas in a closed system in order to avoid, the dangerous handling of pure gas or harmful substances. In the first method, the standardization is based on the in situ formation of carbon monoxide by the reaction of hot concentrated sulfuric acid with formic acid. In the second method, the standardisation is based upon the in situ reduction of ethyl thiocyano by dithiothreitol to produce HCN. In the third method, the standardisation is based upon the in situ chemical transformation of 2-chloro-ethanol into ethylene oxide with a recovery of about 60%.