Sønksen J, Sommer P, Biering-Sørensen F, Ziebe S, Lindhard A, Loft A, Andersen A N, Kristensen J K
Department of Urology, Rigshospitalet, University of Copenhagen, Denmark.
Arch Phys Med Rehabil. 1997 Oct;78(10):1059-61. doi: 10.1016/s0003-9993(97)90127-1.
To present the results of fertility treatment in 28 men with spinal cord injury (SCI) and their partners.
Retrospective analysis.
University hospital outpatient clinic and home.
Twenty-eight anejaculatory men with SCI and their partners seeking treatment for infertility.
Penile vibratory stimulation and electroejaculation as semen retrieval methods. Assisted reproductive techniques used: vaginal self-insemination at home, intrauterine insemination, in vitro fertilization with or without intracytoplasmic sperm injection.
Ejaculation rate; sperm count and motility; pregnancy rates.
All of the men were able to ejaculate either by penile vibratory stimulation (79%) or electroejaculation (21%). Median total sperm count was 65 million (range, 0.1 to 480) with a median motility of 13% (range, 1% to 60%). Overall, 9 of 28 couples (32%) achieved 10 pregnancies (4 self-insemination, 3 intrauterine insemination, 1 in vitro fertilization, and 2 intracytoplasmic sperm injection).
An ejaculation rate of 100% was achieved using penile vibratory stimulation as a first treatment option with electroejaculation as a second option. Motivated couples with adequate semen quality may be offered penile vibratory stimulation combined with self-insemination at home. Together with intrauterine insemination or fertilization techniques used in vitro, the pregnancy rate per treatment cycle for SCI couples may approach that of natural procreation in healthy and fertile couples.
介绍28例脊髓损伤（SCI）男性患者及其伴侣的生育治疗结果。
回顾性分析。
大学医院门诊和家中。
28例患有SCI的不射精男性患者及其寻求不育治疗的伴侣。
采用阴茎振动刺激和电射精作为精液采集方法。使用的辅助生殖技术：在家中进行阴道自我授精、宫内授精、体外受精（有无卵胞浆内单精子注射）。
射精率；精子计数和活力；妊娠率。
所有男性患者均能通过阴茎振动刺激（79%）或电射精（21%）射精。总精子计数中位数为6500万（范围为0.1至480），活力中位数为13%（范围为1%至60%）。总体而言，28对夫妇中有9对（32%）成功妊娠10次（4次自我授精、3次宫内授精、1次体外受精和2次卵胞浆内单精子注射）。
以阴茎振动刺激作为首选治疗方法、电射精作为次选治疗方法，射精率达到了100%。对于有意愿且精液质量足够的夫妇，可采用阴茎振动刺激并结合在家中自我授精。连同宫内授精或体外受精技术一起，SCI夫妇每个治疗周期的妊娠率可能接近健康可育夫妇的自然生育妊娠率。
